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Cephalosporins - 1st Generation WHO AWaRe: Access Prescription only

Cefadroxil — Compare Prices at US & Canada Pharmacies

Compare real Cefadroxil prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives. Save up to 71% by comparing Canada pharmacy prices.

Generic name Cefadroxil
US brand names
Duricef
Also sold as
Apo-Cefadroxil (Canada)
Drug class
1st-generation cephalosporin
Typical course
7–10 daysvaries by infection
Common forms
Capsule, tablet, oral suspension
Generic available
Yeslow cost

How much does cefadroxil (Duricef) cost without insurance?

Generic cefadroxil is typically inexpensive with a discount card. See the pharmacy-by-pharmacy pricing above for real current numbers for your strength and quantity.

Is there a generic version of Duricef?

Yes — generic cefadroxil is what's dispensed by default at most pharmacies.

Do I need a prescription for cefadroxil?

Yes, in the US and Canada. It's not available over the counter.

How can I save on cefadroxil?

Compare discount-card pricing across pharmacies for your exact strength and quantity — the spread can still be meaningful for this generic.

🇺🇸 United States
Lowest found, per pill
$0.61
Oral tablet/capsule, discount-card price
🇨🇦 Canada
Lowest found, per pill
$0.18
Oral tablet/capsule, USD equivalent
Canada is typically cheaper for Cefadroxil Save up to 71%

"As low as" figures compare the single lowest oral tablet/capsule price found on each side — not necessarily the same strength or pack size. Always check the full tables below for your exact dose. Prices updated 2026-08-21.

Cefadroxil prices at US pharmacies

Cefadroxil — capsule, 500mg, qty 14

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $11.57 $8.57
Harris Teeter Pharmacy $11.57 $8.57
Walmart Neighborhood Market $13.59 $10.59
Walmart Pharmacy $13.59 $10.59
Food Lion $12.07
Costco $14.99
Walgreens $19.06 $16.06
Publix $21.87

Cefadroxil prices at Canadian pharmacies

StrengthPharmacyPer pill (USD)Pack total
500 mg CanadianPharmacyAdvantage.com $0.18 $36.31 / 200
500 mg CanadaPharmacies.com $0.23 $46.99 / 200
500 mg CanadianPharmacyAdvantage.com $0.23 $23.27 / 100
500 mg CanadaPharmacies.com $0.34 $33.99 / 100
500 mg LifeRxPharmacy.com $0.37 $33.02 / 90
500 mg LifeRxPharmacy.com $0.44 $26.42 / 60
500 mg InhalersOnline.com $0.51 $45.90 / 90
500 mg SPFPharmacy.com $1.07 $213.78
500 mg SPFPharmacy.com $1.17 $116.76
500 mg InhalersOnline.com $1.22 $121.50

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Cefadroxil used for?

Cefadroxil is a first-generation cephalosporin, closely related to cephalexin, with one practical advantage: a longer half-life that allows once- or twice-daily dosing instead of the every-6-hours schedule cephalexin sometimes requires, which some people find easier to stick to for a full course.

It's used for similar situations as cephalexin — uncomplicated skin infections, strep throat, and uncomplicated UTIs — and shares the same basic coverage gaps, including not reliably covering MRSA, which needs a different antibiotic choice.

As with other cephalosporins, a history of a severe penicillin allergy (anaphylaxis, throat swelling) is worth flagging before starting it, since there's a small but real chance of cross-reactivity.

How Cefadroxil works

  1. Targets the bacterial cell wall

    Cefadroxil is a beta-lactam antibiotic that blocks the enzymes bacteria use to build and maintain their cell wall.

  2. The wall weakens

    Without proper wall construction, the bacterial cell can't withstand internal pressure.

  3. The bacterial cell ruptures

    This direct, bactericidal mechanism kills susceptible bacteria rather than just slowing them down.

Typical dosage forms & strengths

UseTypical adult doseForm
Skin infections, strep throat (adults)500 mg–1 g once or twice dailyCapsule / tablet
Uncomplicated UTI1–2 g once daily, or divided into 2 dosesCapsule / tablet
ChildrenWeight-based (mg/kg/day), once or twice dailyOral suspension

General reference dosing from the FDA label — not personalized advice. Your prescribed dose may differ based on your infection, kidney function, age, and weight. Always follow your prescriber's instructions.

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Common, usually mild

  • Diarrhea
  • Nausea, stomach upset
  • Headache
  • Mild rash

Serious — seek care promptly

  • Severe or watery diarrhea (possible C. diff)
  • Signs of an allergic reaction: hives, facial/throat swelling, trouble breathing
  • Severe skin reaction (blistering, peeling)
  • Unusual bruising or bleeding

Contraindications

Cefadroxil is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.

Warnings

BEFORE THERAPY WITH CEFADROXIL IS INSTITUTED, CAREFUL INQUIRY SHOULD BE MADE TO DETERMINE WHETHER THE PATIENT HAS HAD PREVIOUS HYPERSENSITIVITY REACTIONS TO CEFADROXIL, CEPHALOSPORINS, PENICILLINS, OR OTHER DRUGS. IF THIS PRODUCT IS TO BE GIVEN TO PENICILLIN-SENSITIVE PATIENTS, CAUTION SHOULD BE EXERCISED BECAUSE CROSS-SENSITIVITY AMONG BETA-LACTAM ANTIBIOTICS HAS BEEN CLEARLY DOCUMENTED AND MAY OCCUR IN UP TO 10% OF PATIENTS WITH A HISTORY OF PENICILLIN ALLERGY. IF AN ALLERGIC REACTION TO CEFADROXIL OCCURS, DISCONTINUE THE DRUG.

Notable drug interactions

Drug / substanceWhat can happen
ProbenecidSlows cefadroxil elimination, raising and prolonging blood levels.
Oral contraceptivesRarely reported to reduce effectiveness; a backup method is a reasonable precaution.
WarfarinMay enhance anticoagulant effect in some people; monitoring is a reasonable precaution.
MetforminCephalosporins can modestly raise metformin levels — usually not clinically significant, but worth knowing.

Cefadroxil, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$7.3M
Medicare Part D spend, 2024
537.3K
Medicare Part D claims, 2024
17
FDA-listed manufacturers (Orange Book)
$28.4
Federal (VA) contract price per pack (50)

Frequently asked questions

How much does Cefadroxil cost without insurance?
Retail (no-insurance) prices we found for Cefadroxil range up to about $21.87 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $8.57. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is Cefadroxil cheaper in Canada or the US?
Based on the oral tablet/capsule prices in our data, Canada was cheaper for Cefadroxil — as low as $0.61/pill in the US versus $0.18/pill in Canada, a difference of about 71%. This compares the single lowest price found on each side, not necessarily the same exact strength.
Is there a generic version of Cefadroxil?
Yes — our pricing data includes at least one generic listing for Cefadroxil. Generics contain the same active ingredient and are typically the lowest-cost option; check the price tables above for the generic rows specifically.
What drug class is Cefadroxil in?
Cefadroxil belongs to the cephalosporins - 1st generation class of antibiotics. WHO classifies it as an 'Access' antibiotic under its AWaRe stewardship framework.

Learn more about Cefadroxil

In-depth answers to common Cefadroxil questions, fact-checked against the sources cited in each.

Cephalexin pricing without insurance coverage
  • Cephalexin is a generic antibiotic used to treat various bacterial infections such as strep throat, ear infections, respiratory infections, skin infections, bone infections, and UTIs. It is not effective against viruses and is usually taken every six to twelve hours for a few days.
  • For uninsured patients, the typical cost of cephalexin is around $31 for 28 capsules of 500 mg, with the actual price influenced by dosage, duration of treatment, and the pharmacy chosen.
  • Cephalexin is covered by most major insurance programs, including commercial plans, Medicare Part D, Medicaid, Tricare, and the VA, which can significantly reduce out-of-pocket expenses.
  • Uninsured patients have multiple ways to reduce cephalexin costs, including prescription discount programs, free medication offerings from certain pharmacies, comparing prices across locations, fixed-price generic programs, and accessing medications through 340B clinics and hospitals.

Cephalexin is a prescription generic antibiotic. It is used to treat bacterial infections such as strep throat, ear infections, respiratory infections, skin infections, bone infections, and urinary tract infections (UTIs). As with other antibiotics, cephalexin does not work against viral infections like colds or the flu. Cephalexin is taken by mouth as a tablet, capsule, or liquid suspension, usually every six to 12 hours. The specific dosage and treatment duration depend on the type and severity of the bacterial infection present. Regardless of the prescribed dose, treatment typically lasts only a few days.

Cephalexin is an affordable generic antibiotic with no current brand-name equivalent, though it was historically marketed under the brand name Keflex. While many patients find cephalexin treatment reasonably priced, numerous strategies exist to reduce out-of-pocket expenses even for those without insurance.

Does insurance cover cephalexin?

Cephalexin is an essential and widely prescribed antibiotic. It is usually covered by commercial insurance plans, Medicare Part D, Medicaid, Tricare, and the VA for FDA-approved indications.

What is the cost of cephalexin without insurance?

For those without insurance, the average cash price of cephalexin is about $31 for 28 capsules of 500 mg, which works out to roughly $1 per capsule. For patients taking the medication every six hours, a 28-capsule supply covers approximately one week of treatment. Final costs depend on several factors: the dose prescribed, how frequently it is taken, the total duration of therapy, and the pharmaceutical form. When insurance is available, costs may decrease substantially, though the actual amount paid out-of-pocket will reflect the plan's formulary status, copay amounts, deductible, coinsurance percentage, and for Medicare Part D beneficiaries, the current coverage phase. Insurance companies typically classify cephalexin as a Tier 1 medication, meaning it carries the lowest copay tier.

Because cephalexin is an essential medication, patients unable to afford it should discuss alternative prescription antibiotics with their healthcare provider. Cephalexin belongs to the cephalosporin drug class, which works by preventing bacteria from building and maintaining their protective cell walls. Other cephalosporins like ceftriaxone or cefadroxil are available but generally cost more than cephalexin.

Several other generic antibiotics are less expensive or similarly priced and treat many of the same bacterial infections: amoxicillin, doxycycline, penicillin, ciprofloxacin, and clindamycin are examples. Amoxicillin is often the least costly option. However, patients with penicillin allergies may not tolerate amoxicillin or other penicillin-derived antibiotics. Prescribers select the antibiotic they believe most effective for a given infection; patients should consult their healthcare provider before switching to a different antibiotic based on cost alone.

Over-the-counter medications, supplements, and natural products may ease certain symptoms of bacterial infection but cannot fully eliminate infection the way prescription antibiotics do.

How to obtain cephalexin without insurance

Although cephalexin is an inexpensive, commonly prescribed antibiotic typically needed for only a few days, reducing its cost is still worthwhile for uninsured and insured patients alike. Several practical strategies can help lower prescription expenses.

Use prescription discount programs

Prescription discount programs can significantly reduce the cash price of cephalexin at participating pharmacies. Discount amounts vary by pharmacy and program, so comparing options before filling your prescription can save substantial money. Many programs are free to use and require no enrollment.

Free cephalexin from pharmacies

Many pharmacy chains offer common, essential antibiotics like cephalexin at no cost to uninsured patients who qualify. Eligibility may depend on age, income, or enrollment requirements, so ask your pharmacy or healthcare provider about available programs in your area.

Compare prices across pharmacies

Cephalexin prices vary significantly across pharmacies. Comparing prices at different locations before filling your prescription—either by calling ahead or using online pharmacy price tools—can reveal substantial savings and reduce time spent traveling.

Look for fixed-price generic medication programs

Many major pharmacy chains participate in fixed-price generic programs, often advertising medications at flat rates such as $4 per prescription. Common antibiotics including cephalexin are typically included in these programs. Patients pay the same fixed price regardless of the specific dose prescribed.

Use a 340B clinic or hospital for discounted medications

For low-income patients, 340B program clinics and hospitals dispense common generic drugs like cephalexin at deeply reduced prices or free of charge depending on income level. Contact a local healthcare provider or community health department for a list of 340B providers in your region.


Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.